Cerebroprotective Effect of Moringa oleifera against Focal Ischemic Stroke Induced by Middle Cerebral Artery Occlusion

@inproceedings{Kirisattayakul2013CerebroprotectiveEO,
  title={Cerebroprotective Effect of Moringa oleifera against Focal Ischemic Stroke Induced by Middle Cerebral Artery Occlusion},
  author={Woranan Kirisattayakul and Jintanaporn Wattanathorn and Terdthai Tong-Un and Supaporn Muchimapura and Panakaporn Wannanon and Jinatta Jittiwat},
  booktitle={Oxidative medicine and cellular longevity},
  year={2013}
}
The protection against ischemic stroke is still required due to the limitation of therapeutic efficacy. Based on the role of oxidative stress in stroke pathophysiology, we determined whether Moringa oleifera, a plant possessing potent antioxidant activity, protected against brain damage and oxidative stress in animal model of focal stroke. M. oleifera leaves extract at doses of 100, 200 and 400 mg·kg(-1) was orally given to male Wistar rats (300-350 g) once daily at a period of 2 weeks before… CONTINUE READING
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