Cerebral white matter lesions and the risk of dementia.

  title={Cerebral white matter lesions and the risk of dementia.},
  author={Niels Dani{\"e}l Prins and Ewoud J van Dijk and Tom den Heijer and Sarah E. Vermeer and Peter J Koudstaal and Matthijs Oudkerk and Albert Hofman and Monique M B Breteler},
  journal={Archives of neurology},
  volume={61 10},
  • Niels Daniël Prins, Ewoud J van Dijk, +5 authors Monique M B Breteler
  • Published 2004 in Archives of neurology
OBJECTIVE To study the association between white matter lesions (WML) in specific locations and the risk of dementia. DESIGN The Rotterdam Scan Study, a prospective population-based cohort study. We scored periventricular and subcortical WML on magnetic resonance imaging and observed participants until January 2002 for incident dementia. SETTING General population. PARTICIPANTS We included 1077 people aged 60 to 90 years who did not have dementia at baseline. MAIN OUTCOME MEASURE… CONTINUE READING

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