Cerebral responses and role of the prefrontal cortex in conditioned pain modulation: an fMRI study in healthy subjects.


The mechanisms underlying conditioned pain modulation (CPM) are multifaceted. We searched for a link between individual differences in prefrontal cortex activity during multi-trial heterotopic noxious cold conditioning and modulation of the cerebral response to phasic heat pain. In 24 healthy female subjects, we conditioned laser heat stimuli to the left… (More)
DOI: 10.1016/j.bbr.2014.11.028


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