Cerebral perfusion correlates of depressed mood.

  title={Cerebral perfusion correlates of depressed mood.},
  author={Klaus P. Ebmeier and Jonathan T O Cavanagh and Anthony P. R. Moffoot and Mike F. Glabus and Ronan E O'Carroll and Guy M. Goodwin},
  journal={The British journal of psychiatry : the journal of mental science},
BACKGROUND The spontaneous diurnal variation of mood and other symptoms provides a substrate for the examination of the relationship between symptoms and regional brain activation in depression. METHOD Twenty unipolar depressed patients with diurnal variation of mood were examined at 8 a.m. and 8 p.m. with neuropsychological measures, clinical ratings and single photon emission tomography (SPET). Brain perfusion maps were spatially transformed into standard stereotactic space and compared… CONTINUE READING


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