Cerebral pattern of pro- and anti-inflammatory cytokines in dementias.

  title={Cerebral pattern of pro- and anti-inflammatory cytokines in dementias.},
  author={Elisabeth Tarkowski and Ann Marie Liljeroth and Lennart Minthon and Andrzej Tarkowski and Anders Wallin and K Blennow},
  journal={Brain research bulletin},
  volume={61 3},
The knowledge regarding putative inflammatory component(s) participating in Alzheimer's disease (AD) and vascular dementia (VAD) is scarce. Recently, we have demonstrated the presence of certain inflammatory cytokines in the cerebrospinal fluid (CSF) of demented patients. Although the initial event(s) triggering the neurodegenerative processes in AD versus VAD may be different and lead to different neuropathological changes, it may initiate a similar cascade of cytokine production in response… CONTINUE READING