Cerebral oxygenation and the recoverable brain.

  title={Cerebral oxygenation and the recoverable brain.},
  author={Richard A. Neubauer and Philip P B James},
  journal={Neurological research},
  volume={20 Suppl 1},
Oxygenation is the most critical function of blood flow and a sudden reduction in oxygen availability is an inevitable consequence of severe ischemia. The resulting cascade of events may result in the failure of membrane integrity of some cells and necrosis, but in the surrounding zone of tissue, less affected by hypoxia, cells survive to form the ischemic penumbra. The timing of these events is uncertain, but sufficient oxygen is available to these cells to maintain membrane ion pump… CONTINUE READING


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