Cerebral oxygen metabolism in neonatal hypoxic ischemic encephalopathy during and after therapeutic hypothermia.

@article{Dehaes2014CerebralOM,
  title={Cerebral oxygen metabolism in neonatal hypoxic ischemic encephalopathy during and after therapeutic hypothermia.},
  author={Mathieu Dehaes and Alpna Aggarwal and Pei-Yi Lin and C Rosa Fortuno and Angela Fenoglio and Nadege Roche-Labarbe and J. S. Soul and Maria Angela Franceschini and P. Ellen Grant},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2014},
  volume={34 1},
  pages={87-94}
}
Pathophysiologic mechanisms involved in neonatal hypoxic ischemic encephalopathy (HIE) are associated with complex changes of blood flow and metabolism. Therapeutic hypothermia (TH) is effective in reducing the extent of brain injury, but it remains uncertain how TH affects cerebral blood flow (CBF) and metabolism. Ten neonates undergoing TH for HIE and seventeen healthy controls were recruited from the NICU and the well baby nursery, respectively. A combination of frequency domain near… CONTINUE READING

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