Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases.

@article{Grammas2011CerebralME,
  title={Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases.},
  author={Paula Grammas and Joseph Martinez and Bradley M. Miller},
  journal={Expert reviews in molecular medicine},
  year={2011},
  volume={13},
  pages={e19}
}
Diseases of the central nervous system (CNS) pose a significant health challenge, but despite their diversity, they share many common features and mechanisms. For example, endothelial dysfunction has been implicated as a crucial event in the development of several CNS disorders, such as Alzheimer disease, Parkinson disease, amyotrophic lateral sclerosis, multiple sclerosis, human immunodeficiency virus (HIV)-1-associated neurocognitive disorder and traumatic brain injury. Breakdown of the blood… CONTINUE READING

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