Cerebral microdialysis methodology--evaluation of 20 kDa and 100 kDa catheters.

  title={Cerebral microdialysis methodology--evaluation of 20 kDa and 100 kDa catheters.},
  author={Peter J Hutchinson and Mark T O'Connell and J{\"u}rgens Nortje and Phil Smith and Pippa G. Al-Rawi and Arun Kumar Gupta and David K. Menon and John D. Pickard},
  journal={Physiological measurement},
  volume={26 4},
Microdialysis monitoring of cerebral metabolism is now performed in several neuro-intensive care units. Conventional microdialysis utilizes CMA70 catheters with 20 kDa molecular weight cut-off membranes enabling the measurement of small molecules such as glucose, lactate, pyruvate and glutamate. The CMA71 100 kDa molecular weight cut-off microdialysis catheter has recently been introduced to allow detection of larger molecules such as cytokines. The objective of this study was to perform in… CONTINUE READING
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