Cerebral metabolism in opiate-dependent subjects: effects of methadone maintenance.

  title={Cerebral metabolism in opiate-dependent subjects: effects of methadone maintenance.},
  author={Igor I. Galynker and S Watras-Ganz and Christian R. Miner and Richard N. Rosenthal and Don C Des Jarlais and Beverly L. Richman and Emily London},
  journal={The Mount Sinai journal of medicine, New York},
  volume={67 5-6},
BACKGROUND The long-term effects of opiate use on human brain are not known. The goal of this preliminary study was to determine whether human subjects with histories of opiate dependence have persistent differences in brain function as compared with individuals without substance use disorders, and whether methadone maintenance reverses or ameliorates the potential abnormality. METHOD Positron emission tomographic (PET) [18F]fluorodeoxyglucose (FDG) method was used to compare the regional… CONTINUE READING

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  • J Consult Clin Psychol
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