Cerebral metabolism during cord occlusion and hypoxia in the fetal sheep: a novel method of continuous measurement based on heat production.

@article{Hunter2003CerebralMD,
  title={Cerebral metabolism during cord occlusion and hypoxia in the fetal sheep: a novel method of continuous measurement based on heat production.},
  author={Christian J. Hunter and Arlin B. Blood and Gordon Power},
  journal={The Journal of physiology},
  year={2003},
  volume={552 Pt 1},
  pages={
          241-51
        }
}
This study was undertaken to validate a new method of measuring cerebral metabolic rate in the fetal sheep based on heat production in a local region of the brain. Heat production was compared to oxygen use in 20 near-term fetuses during basal conditions, moderate hypoxia and cord occlusion. Thermocouples were placed to measure core and brain temperature and a composite probe placed in the parietal cortex to measure changes in cortical blood flow (CBF) using laser Doppler flowmetry and tissue… CONTINUE READING
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