Cerebral metabolic rate in hypercapnia: controversy continues.

@article{Yablonskiy2011CerebralMR,
  title={Cerebral metabolic rate in hypercapnia: controversy continues.},
  author={Dmitriy A. Yablonskiy},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2011},
  volume={31 7},
  pages={1502-3}
}
Thirty years ago, a publication by Seisjo, entitled ‘Cerebral metabolic rate in hypercarbia—a controversy’ summarized the current state of knowledge related to the influence of hypercapnia (increased pCO2) on cerebral metabolic rate of oxygen consumption (CMRO2) (Siesjo, 1980). Seisjo quoted a number of papers that provided controversial results ranging from reduced, to unchanged, to increased CMRO2 and concluded his paper with the following comment: ‘Since hypercarbia is a common… CONTINUE READING

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