Cerebral malaria in inbred mice. I. A new model and its pathology.

@article{Rest1982CerebralMI,
  title={Cerebral malaria in inbred mice. I. A new model and its pathology.},
  author={Joan R Rest},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  year={1982},
  volume={76 3},
  pages={410-5}
}
  • Joan R Rest
  • Published 1982 in
    Transactions of the Royal Society of Tropical…
Plasmodium berghei ANKA was tested for its usefulness as a model for cerebral malaria in inbred mouse strains A, A2G, A/J, C57L, SJL/J and SWR. A suitable model was obtained in A or A/J strain mice. Mortality was 100% after five to eight days with brain haemorrhages occurring terminally. The histopathology is described. The model was stable after six blood passages at 5- to 7-day intervals. Chloroquine abolished the haemorrhages and no intercurrent viral or blood protozoal infections were… CONTINUE READING

From This Paper

Topics from this paper.
58 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 58 extracted citations

Similar Papers

Loading similar papers…