Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease.

@article{Suter2002CerebralHG,
  title={Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease.},
  author={O C Suter and Thanomphone Sunthorn and Rudolf Kraftsik and Joel Straubel and Pushpa Darekar and Kamel Khalili and Judith Miklossy},
  journal={Stroke},
  year={2002},
  volume={33 8},
  pages={1986-92}
}
BACKGROUND AND PURPOSE The watershed cortical areas are the first to be deprived of sufficient blood flow in the event of cerebral hypoperfusion and will be the sites of watershed microinfarcts. Cerebral hypoperfusion is associated with Alzheimer disease (AD), but information regarding the occurrence of watershed cortical infarcts in AD is lacking. METHODS Brains of 184 autopsy cases (105 definite AD cases and 79 age-matched controls) were selected and analyzed by histochemical and… CONTINUE READING

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