Cerebral hemodynamics, oxygen uptake and cerebral arteriovenous differences of catecholamines following E. coli endotoxin in dogs.

@article{Ekstrmjodal1982CerebralHO,
  title={Cerebral hemodynamics, oxygen uptake and cerebral arteriovenous differences of catecholamines following E. coli endotoxin in dogs.},
  author={B Ekstr{\"o}m-jodal and Jan H{\"a}ggendal and Lars Larsson and Andreas Westerlind},
  journal={Acta anaesthesiologica Scandinavica},
  year={1982},
  volume={26 5},
  pages={446-52}
}
In experimental endotoxic shock in dogs, a decrease in cerebral blood flow and an increase in cerebral metabolic rate of oxygen (CMRO2) have been shown to occur. In this situation the blood levels of adrenaline and noradrenaline are markedly elevated. The aim of the present study was to investigate whether a cerebral uptake of circulating catecholamines with a possible influence on CMRO2 takes place in the brain. In eight anaesthetized dogs, arterial blood, superior sagittal sinus blood and… CONTINUE READING