Cerebral haemodynamic effects of dihydroergotamine in patients with severe traumatic brain lesions.

@article{Asgeirsson1995CerebralHE,
  title={Cerebral haemodynamic effects of dihydroergotamine in patients with severe traumatic brain lesions.},
  author={B. Asgeirsson and Per Olof Gr{\"a}nde and C. H. Nordstr{\"o}m and Kenneth Messeter and Hans Sj{\"o}holm},
  journal={Acta anaesthesiologica Scandinavica},
  year={1995},
  volume={39 7},
  pages={922-30}
}
Dihydroergotamine (DHE) is used in our recently introduced therapy of post-traumatic brain oedema and is suggested to reduce ICP through reduction in both cerebral blood volume and brain water content. This study aims at increasing our knowledge of the mechanisms behind the ICP reducing effect of DHE by analysing cerebrovascular effects of a bolus dose of DHE in severely head injured patients (GCS < 8). Mean hemispheric cerebral blood flow (CBF) calculated from the clearance of i.v. 133Xenon… CONTINUE READING