Cerebral function in posttraumatic stress disorder during verbal working memory updating: a positron emission tomography study.

@article{Clark2003CerebralFI,
  title={Cerebral function in posttraumatic stress disorder during verbal working memory updating: a positron emission tomography study.},
  author={C. Richard Clark and Alexander C Mcfarlane and P. Sean Morris and Darren L. Weber and Cynon Sonkkilla and Marnie E. Shaw and Jackie Marcina and Henri Jacques Tochon-Danguy and Gary F. Egan},
  journal={Biological psychiatry},
  year={2003},
  volume={53 6},
  pages={474-81}
}
BACKGROUND This study examined cerebral function in posttraumatic stress disorder (PTSD) during the updating of working memory to trauma-neutral, verbal information. METHODS Ten PTSD and matched control subjects completed a visuoverbal target detection task involving continuous updating (Variable target condition) or no updating (Fixed target condition) of target identity, with updating activity estimated by condition comparison. RESULTS Normal updating activity using this paradigm involved… CONTINUE READING

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