Cerebral diffusion and T(2): MRI predictors of acute mountain sickness during sustained high-altitude hypoxia.

@article{Hunt2013CerebralDA,
  title={Cerebral diffusion and T(2): MRI predictors of acute mountain sickness during sustained high-altitude hypoxia.},
  author={John S. Hunt and Rebecca J. Theilmann and Zachary M Smith and Miriam Scadeng and David J. Dubowitz},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2013},
  volume={33 3},
  pages={372-80}
}
Diffusion magnetic resonance imaging (MRI) provides a sensitive indicator of cerebral hypoxia. We investigated if apparent diffusion coefficient (ADC) and transverse relaxation (T(2)) predict symptoms of acute mountain sickness (AMS), or merely indicate the AMS phenotype irrespective of symptoms. Fourteen normal subjects were studied in two groups; unambiguous AMS and no-AMS at 3,800 m altitude (intermediate AMS scores were excluded). T(2) relaxation was estimated from a T(2) index of T(2… CONTINUE READING
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