Cerebral cortex: An MRI-based study of volume and variance with age and sex

  title={Cerebral cortex: An MRI-based study of volume and variance with age and sex},
  author={Ross P. Carne and Simon J. Vogrin and Lucas Litewka and Mark J. Cook},
  journal={Journal of Clinical Neuroscience},

Age related FLAIR-MRI brain cortical changes in normal aging: central tendency versus dispersion values

The aim was to use central tendency and dispersion values of T2-FLAIR-MRI signal intensity profiles from frontal, parietal, occipital and cingulate cortices and correlate them with age and gender to detect abnormal age-related cortical changes.

Stereological evaluation of volumetric asymmetry in healthy human cerebellum

The stereological evaluation of cerebellar asymmetry in humans correlate with both gender and age groups is of importance for both clinicians and anatomists and the technique is simple, reliable, unbiased and inexpensive.

White Matter Sexual Dimorphism of the Adult Human Brain

A voxel-based morphometry (VBM) analysis along with global volume analysis for white matter across sex found males to have larger WM, compared to females, in occipital, temporal, insular, parietal, and frontal brain regions.

Age-related gray matter volume changes in the brain during non-elderly adulthood

A Cross-Sectional Voxel-Based Morphometric Study of Age- and Sex-Related Changes in Gray Matter Volume in the Normal Aging Brain

The voxel-based morphometry approach may provide an emerging paradigm in the normal aging brain that may help differentiate underlying normal neurobiological aging changes of specific brain regions from neurodegenerative impairments.

The volume fraction of brain ventricles to total brain volume: a computed tomography stereological study.

The mean percentage of total ventricle volume within the total brain volume was found to be 2%, and the volume fraction of total Ventricle to total brain in normal subjects was demonstrated.

Male prevalent enhancement of leftward asymmetric development of the cerebellar cortex in ferrets (Mustela putorius)

The present results suggest that sexual dimorphism of the ferret cerebellum is characterized by enhancing the leftward laterality in the CZp in males, forming the distinctive counterclockwise torque asymmetry.



Normal neuroanatomical variation in the human brain: an MRI-volumetric study.

High-resolution magnetic resonance imaging was used to measure regional brain volumes in 46 normal, right-handed adults between the ages of 22-49 years, and results have implications for understanding whether or not certain sectors of the brain have shown relative expansion over the course of hominid and hominoid evolution.

Sex differences in aging of the human frontal and temporal lobes

Age-related reductions in both regions were greater in men than in women, demonstrating that sexual dimorphisms in human neuroanatomy are not fixed, but continue to change throughout adulthood.

Sex differences in brain aging: a quantitative magnetic resonance imaging study.

The results are generally consistent with the few published studies on sex differences in brain aging and suggest that, for at least some structures, aging effects may be more apparent in men than women.

Intelligence and brain structure in normal individuals.

The results suggest that the size of some cerebral structures may account for a significant, but modest, proportion of the variance in human intelligence.

Sex Differences in Brain Gray and White Matter in Healthy Young Adults: Correlations with Cognitive Performance

Both GM and WM volumes correlated moderately with global, verbal, and spatial performance across groups, however, the regression of cognitive performance and WM volume was significantly steeper in women.

Selective aging of the human cerebral cortex observed in vivo: differential vulnerability of the prefrontal gray matter.

Small but consistent rightward asymmetry was found in the whole cerebral hemispheres, superior parietal, fusiform and orbito-frontal cortices, postcentral and prefrontal white matter, and in the parietal white matter.

Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging.

A permutation test showed that, compared to other brain areas assessed in this study, there was greater sexual dimorphism among brain areas that are homologous with those identified in animal studies showing greater levels of sex steroid receptors during critical periods of brain development.

Age and sex differences in the cerebellum and the ventral pons: a prospective MR study of healthy adults.

Moderate age-related shrinkage of the cerebellum and lack of age- related differences in the ventral pons are robust phenomena, however, in all likelihood, the effects of age on the Cerebellum are not differential but uniform.