Cerebral cavernous malformations: congruency of histopathological features with the current clinical definition

  title={Cerebral cavernous malformations: congruency of histopathological features with the current clinical definition},
  author={Josa M. Frischer and Iris Pipp and Ioannis Stavrou and Siegfried Trattnig and J. Hainfellner and Engelbert Knosp},
  journal={Journal of Neurology, Neurosurgery, and Psychiatry},
  pages={783 - 788}
Aim: Cerebral cavernous malformations (CCMs) are defined as a mulberry-like assembly of thin walled vascular sinusoids lined by a thin endothelium lacking smooth muscle and elastin, displaying no intervening brain parenchyma. In this study, we analyse the congruency of histopathological features with the current clinical definition on a large series of neuroradiologically verified CCMs. Methods: 87 patients who received no primary treatment prior to surgery were included. Preoperative MRIs of… 

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