Cerebral blood flow following indomethacin administration.


Cerebral hemodynamics were studied in 7 term newborn lambs and 10 preterm infants with patent ductus arteriosus. Intracranial blood flow velocities were measured using a pulsed-wave Doppler velocimeter applied through the fontanel. Intravenous injection of indomethacin (0.2 mg.kg-1) reduced intracranial blood flow velocities in both lambs and infants. The… (More)


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