Cerebral blood flow changes in man by wake-promoting drug, modafinil: a randomized double blind study.

@article{Joo2008CerebralBF,
  title={Cerebral blood flow changes in man by wake-promoting drug, modafinil: a randomized double blind study.},
  author={Eun Yeon Joo and Woo Suk Tae and Ki-Young Jung and Seung Bong Hong},
  journal={Journal of sleep research},
  year={2008},
  volume={17 1},
  pages={82-8}
}
To investigate the effects of a wake-promoting drug, modafinil on regional cerebral blood flow (rCBF) in healthy volunteers, we performed (99m)Tc-ethylcysteinate dimer single photon emission computed tomography (SPECT) before and after modafinil or placebo administration. Twenty-one healthy subjects received single doses of 400 mg modafinil or placebo in a… CONTINUE READING