Topics from this paper
Physiology of the cerebrovascular adaptation to pregnancy.
- Handbook of clinical neurology
In this chapter, the effect of pregnancy on critical functions of the cerebral circulation is discussed, including changes occurring at the endothelium and blood-brain barrier (BBB), which protect the maternal brain from changes in BBB permeability. Expand
Cerebrovascular Pathophysiology in Preeclampsia and Eclampsia
Animal studies highlight several underlying mechanisms by which pregnancy and experimental preeclampsia influence cerebrovascular structure and function and bears important implications for current pathophysiologic, preventive, and therapeutic concepts of eClampsia. Expand
Mechanisms of Seizure during Pregnancy and Preeclampsia
Evidence is provided that pregnancy increases susceptibility of the brain to seizure and vasogenic edema formation that likely contribute to the onset of eclampsia during seemingly uncomplicated pregnancies. Expand
The cerebral circulation during pregnancy: adapting to preserve normalcy.
The effect of pregnancy on critical functions of the cerebral circulation is discussed, including changes occurring at the endothelium and blood-brain barrier, and changes in the structure and function of cerebral arteries and arterioles, hemodynamics, and cerebral blood flow autoregulation. Expand
Effect of Pregnancy and Nitric Oxide on the Myogenic Vasodilation of Posterior Cerebral Arteries and the Lower Limit of Cerebral Blood Flow Autoregulation
- Reproductive Sciences
Pregnancy enhanced myogenic vasodilation in PCA and shifted the lower limit of CBF autoregulation to lower pressures, likely protective of ischemic injury during hemorrhage and appears to be independent of NOS. Expand
Anatomical, Physiological and Metabolic Changes with Gestational Age during Normal Pregnancy
- Biology, Medicine
- Clinical Pharmacokinetics
The collected data presented in this paper provide a potentially useful singular resource for key parameters needed for PBPK modelling in pregnancy, which facilitates the risk assessment of environmental chemicals and therapeutic drug dose adjustments in the pregnant population. Expand
Physiologic changes during normal pregnancy and delivery.
- Cardiology clinics
The major adaptations of the maternal cardiovascular system that progress throughout gestation may unmask previously unrecognized heart disease and result in significant morbidity and mortality. Most… Expand
Cerebrovascular (Patho)Physiology in Preeclampsia/Eclampsia
This chapter coorelates neuropathological observations of eclampsia with the noninvasive imaging findings derived from CT scanning and MR imaging and correlates cerebrovascular abnormalities induced by preeclampsian syndrome with direct and indirect nonin invasive methods such as MR technology and Doppler velocimetry. Expand
[Hypertension and pregnancy].
- Archivos de cardiologia de Mexico
Women at high risk must be monitored closely for conventional risk factors that are common to both CVD and hypertensive disorders of pregnancy and treated according to current evidence-based national guidelines. Expand
Magnetic resonance imaging and cerebrovascular hemodynamics in (pre)-eclampsia
Hoge bloeddruk tijdens de zwangerschap is gevaarlijk. De mogelijke gevolgen, zoals hersenoedeem, stuipen en hersenbloedingen, eisen jaarlijks wereldwijd 50 tot 65 duizend vrouwenlevens. Ook in… Expand