Cerebral blood flow MRI in mice using the cardiac-spin-labeling technique.

  title={Cerebral blood flow MRI in mice using the cardiac-spin-labeling technique.},
  author={Eric R. Muir and Qiang Shen and Timothy Q. Duong},
  journal={Magnetic resonance in medicine},
  volume={60 3},
Continuous arterial spin labeling MRI with a separate neck labeling coil provides a highly sensitive method to image cerebral blood flow (CBF). In mice, however, this has not been possible because the proximity of the neck coil to the brain uses the neck coil to significantly saturate the brain signal. To overcome this limitation the cardiac spin labeling (CSL) technique is introduced in which the labeling coil is placed at the heart position. To demonstrate its utility, CSL CBF was applied to… CONTINUE READING

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