Cerebral arterial pathology of CADASIL and CARASIL (Maeda syndrome).

@article{Arima2003CerebralAP,
  title={Cerebral arterial pathology of CADASIL and CARASIL (Maeda syndrome).},
  author={Kunimasa Arima and Sohei Yanagawa and Nobuo Ito and Shu-ichi Ikeda},
  journal={Neuropathology : official journal of the Japanese Society of Neuropathology},
  year={2003},
  volume={23 4},
  pages={327-34}
}
Two familial cerebro-vascular diseases characterized by different cerebral arterial pathologies and presenting in non-hypertensive young and middle-aged adults are described. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is characterized by the deposition of smudged periodic acid-Schiff (PAS)-positive granules known as granular osmiophilic materials (GOM) in the media of small arteries and arterioles. The medial smooth muscle cells are… CONTINUE READING