Cerebral amyloid-beta protein accumulation with aging in cotton-top tamarins: a model of early Alzheimer's disease?

@article{Lemere2008CerebralAP,
  title={Cerebral amyloid-beta protein accumulation with aging in cotton-top tamarins: a model of early Alzheimer's disease?},
  author={Cynthia A Lemere and Jiwon Oh and Heather A Stanish and Y. N. Peng and Imelda Pepivani and Anne M. Fagan and Haruyasu Yamaguchi and Susan. V. Westmoreland and Keith G Mansfield},
  journal={Rejuvenation research},
  year={2008},
  volume={11 2},
  pages={321-32}
}
Alzheimer's disease (AD) is the most common progressive form of dementia in the elderly. Two major neuropathological hallmarks of AD include cerebral deposition of amyloid-beta protein (Abeta) into plaques and blood vessels, and the presence of neurofibrillary tangles in brain. In addition, activated microglia and reactive astrocytes are often associated… CONTINUE READING