Cerebral amyloid angiopathy and its relationship to Alzheimer’s disease

  title={Cerebral amyloid angiopathy and its relationship to Alzheimer’s disease},
  author={D. Thal and W. Griffin and R. Vos and E. Ghebremedhin},
  journal={Acta Neuropathologica},
  • D. Thal, W. Griffin, +1 author E. Ghebremedhin
  • Published 2008
  • Biology, Medicine
  • Acta Neuropathologica
  • Cerebral amyloid angiopathy (CAA) is characterized by the deposition of the amyloid β-protein (Aβ) within cerebral vessels. The involvement of different brain areas in CAA follows a hierarchical sequence similar to that of Alzheimer-related senile plaques. Alzheimer’s disease patients frequently exhibit CAA. The expansion of CAA in AD often shows the pattern of full-blown CAA. The deposition of Aβ within capillaries distinguishes two types of CAA. One with capillary Aβ-deposition is… CONTINUE READING
    Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts
    • 128
    • PDF
    Cerebral amyloid angiopathy as a cause of neurodegeneration
    • 19
    Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies
    • 207


    Publications referenced by this paper.
    Two Types of Sporadic Cerebral Amyloid Angiopathy
    • 233
    • PDF
    Cerebral Amyloid Angiopathies: A Pathologic, Biochemical, and Genetic View
    • 260
    • Highly Influential
    • PDF
    Brain Parenchymal and Microvascular Amyloid in Alzheimer's Disease
    • 169
    Only cerebral capillary amyloid angiopathy correlates with Alzheimer pathology—a pilot study
    • 135
    Alzheimer disease and cerebrovascular pathology: an update
    • 535