Cerebral amyloid β(42) deposits and microvascular pathology in ageing baboons.

  title={Cerebral amyloid β(42) deposits and microvascular pathology in ageing baboons.},
  author={Mary W Ndung'u and Wolfgang H{\"a}rtig and Florian Wegner and Jason M. Mwenda and Roger Wee Chuang Low and Rufus O Akinyemi and Raj N Kalaria},
  journal={Neuropathology and applied neurobiology},
  volume={38 5},
BACKGROUND Previous studies have extensively reported the deposition of amyloid β (Aβ) peptide with carboxyl- and amino-terminal heterogeneity in cortical and cerebrovascular deposits in Alzheimer's disease (AD) and in non-human primates except baboons. METHODS We examined the immunocytochemical distribution of Aβ peptides and Aβ oligomers in brain tissue from three subspecies of 18- to 28-year-old baboons (Papio) and in other monkeys including the squirrel (Saimiri sciureus) and rhesus… CONTINUE READING
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