Cerebral Metabolism within 18 Hours of Birth Asphyxia: A Proton Magnetic Resonance Spectroscopy Study

@article{Hanrahan1996CerebralMW,
  title={Cerebral Metabolism within 18 Hours of Birth Asphyxia: A Proton Magnetic Resonance Spectroscopy Study},
  author={Jeffery D. Hanrahan and Janet Sargentoni and Denis Victor Azzopardi and Karim A. Manji and Frances M Cowan and Mary A. Rutherford and I Jane Cox and Jimmy D. Bell and David James Bryant and A. David Edwards},
  journal={Pediatric Research},
  year={1996},
  volume={39},
  pages={584-590}
}
Proton magnetic resonance spectroscopy (1H MRS) was performed within 18 h of birth (median 13, range 4-18 h) on 16 term infants with clinical features of birth asphyxia. Ten infants with no evidence of birth asphyxia were studied as controls at 5-18 (median 8) h after birth. To detect delayed impairments in cerebral energy metabolism, 15 infants suspected of asphyxia underwent 31P MRS at 33-106 (median 62) h of age. Choline, creatine, and N-acetylaspartate (NAA) were detected in spectra located… CONTINUE READING
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