Cerebral MRI abnormalities associated with vigabatrin therapy.

  title={Cerebral MRI abnormalities associated with vigabatrin therapy.},
  author={Phillip Lawrence Pearl and L. Gilbert Vezina and R P Saneto and Robert Mccarter and Elizabeth Molloy-Wells and Ari M Heffron and Stacey Trzcinski and William M McClintock and Joan A Conry and Nancy J Elling and Howard P Goodkin and M{\'a}rcio A Sotero de Menezes and Raymond T. Ferri and Elizabeth Gilles and N Kadom and William D. Gaillard},
  volume={50 2},
PURPOSE Investigate whether patients on vigabatrin demonstrated new-onset and reversible T(2)-weighted magnetic resonance imaging (MRI) abnormalities. METHODS MRI of patients treated during vigabatrin therapy was reviewed, following detection of new basal ganglia, thalamus, and corpus callosum hyperintensities in an infant treated for infantile spasms. Patients were assessed for age at time of MRI, diagnosis, duration, and dose, MRI findings pre-, on, and postvigabatrin, concomitant… CONTINUE READING
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Cerebral MRI abnormalities

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Basal ganglia injury

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