Cerebral Amyloid Angiopathy-Related Microbleeds Correlate with Glucose Metabolism and Brain Volume in Alzheimer's Disease.

@article{Samuraki2015CerebralAA,
  title={Cerebral Amyloid Angiopathy-Related Microbleeds Correlate with Glucose Metabolism and Brain Volume in Alzheimer's Disease.},
  author={M Samuraki and I Matsunari and Mitsuhiro Yoshita and Keisuke Shima and M Noguchi-Shinohara and Tsuyoshi Hamaguchi and Kenjiro Ono and M-A. Yamada},
  journal={Journal of Alzheimer's disease : JAD},
  year={2015},
  volume={48 2},
  pages={
          517-28
        }
}
BACKGROUND Microbleeds (MBs) are frequently observed in Alzheimer's disease (AD); however, the relevance to AD pathophysiology has not been elucidated. OBJECTIVES We investigated correlation of MBs, especially cerebral amyloid angiopathy (CAA)-related MBs with cognitive function, gray matter volume, and glucose metabolism in AD. METHODS We performed magnetic resonance imaging including T2*-weighted imaging sequence for 206 patients with AD. Among them, 158 AD patients with no focal brain… CONTINUE READING
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