Cerebellum-like structures and their implications for cerebellar function.

  title={Cerebellum-like structures and their implications for cerebellar function.},
  author={Curtis C. Bell and Victor Z. Han and Nathaniel B. Sawtell},
  journal={Annual review of neuroscience},
The nervous systems of most vertebrates include both the cerebellum and structures that are architecturally similar to the cerebellum. The cerebellum-like structures are sensory structures that receive input from the periphery in their deep layers and parallel fiber input in their molecular layers. This review describes these cerebellum-like structures and compares them with the cerebellum itself. The cerebellum-like structures in three groups of fish act as adaptive sensory processors in which… 

Figures from this paper

The Cerebellum and Cerebellum-Like Structures of Cartilaginous Fishes

The cerebellum is an evolutionary innovation in gnathostomes that is literally superimposed on pre-existing underlying brain structures and pathways and can be considered an example of ‘subsumption architecture’, a term that describes the addition of modules that add computational power while maintaining existing fundamental functionality.

Adaptive processing in electrosensory systems: Links to cerebellar plasticity and learning

Functional origins of the vertebrate cerebellum from a sensory processing antecedent

Good progress has been made in determining the fundamental processing algorithm in cerebellar-like structures, and the authors have come to understand the contribution to signal processing made by the molecular layer, which provides an adaptive filter to cancel self-generated noise in electrosensory and lateral line systems.

Physiology of the cerebellum.

Development of the cerebellum and cerebellar neural circuits

The anatomy and development of cerebellar neurons and their circuitry are described, and the possible roles of the cerebellum and Cerebellum‐like structures in behavior and higher cognitive functions are discussed.

A comparative approach to cerebellar function: insights from electrosensory systems

Are mushroom bodies cerebellum-like structures?

  • S. Farris
  • Biology
    Arthropod structure & development
  • 2011

Deciphering Cerebellar Neural Circuitry Involved in Higher Order Functions Using the Zebrafish Model

This chapter focuses on the cerebellum, which is derived from the dorsal part of the most anterior hindbrain and is involved in motor control and higher cognitive/emotional functions and describes the structure and development processes in zebrafish and compared with those in mammals.

The Cerebellum

In addition to its direct role in motor control, the cerebellum is necessary for several types of motor learning, most notably learning to adjust to changes in sensorimotor relationships.

Optimal routing to cerebellum-like structures

A general theory of cerebellum-like structures in conjunction with their afferent pathways is developed that predicts the role of the pontine relay to cerebellar cortex and the glomerular organization of the insect antennal lobe and shows that structured compression followed by random expansion is an efficient architecture for flexible computation.



Evolution of Cerebellum-Like Structures

  • C. Bell
  • Biology
    Brain, Behavior and Evolution
  • 2002
Physiological findings from three different systems suggest the hypothesis that cerebellum-like structures remove predictable features from the sensory inflow and evolutionary convergence provides the best explanation for all these similarities that cannot be explained by homology.

Is the cerebellum like cerebellar-like structures?

  • A. Devor
  • Biology
    Brain Research Reviews
  • 2000

The role of the cerebellum in motor control and perception.

  • M. Paulin
  • Psychology, Biology
    Brain, behavior and evolution
  • 1993
Evidence reviewed in this paper shows that the cerebellum is associated with sensory systems used for tracking movements of targets in the environment, as well as movements made by the animal itself, in all vertebrates, not just in a few isolated cases.

What the cerebellum computes

Cerebellar circuits and synaptic mechanisms involved in classical eyeblink conditioning

The Cochlear Nucleus: Neuronal Types and Their Synaptic Organization

The auditory system, like other sensory systems, comprises multiple neuronal pathways, each conveying information from the periphery to the forebrain via distinct sets of neurons and each with its

The generation and subtraction of sensory expectations within cerebellum-like structures.

The generation of sensory expectations within cerebellum-like structures of four distinct groups of fishes, including Mormyridae; Rajidae; Scorpaenidae; and Apteronotidae, is described and it is indicated that the negative image is probably generated by means of anti-Hebbian synaptic plasticity at the parallel fiber to principal cell synapse.

Expression of zebrafish glutamate receptor delta2 in neurons with cerebellum-like wiring.

The Purkinje cell class may extend beyond the cerebellum

It is demonstrated for the first time that three independent murine mutations, Lurcher, Purkinje cell degeneration and Staggerer, which result in the postnatal degeneration of Purkinja cells, also cause the elimination of cartwheel cells of the dorsal cochlear nucleus.

Bidirectional synaptic plasticity in the cerebellum-like mammalian dorsal cochlear nucleus

  • K. FujinoD. Oertel
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2002
The dorsal cochlear nucleus integrates acoustic with multimodal sensory inputs from widespread areas of the brain and its sensitivity to antagonists of N-methyl-d-aspartate and metabotropic glutamate receptors differs in fusiform and cartwheel cells.