Cerebellum-dependent learning: the role of multiple plasticity mechanisms.

@article{Boyden2004CerebellumdependentLT,
  title={Cerebellum-dependent learning: the role of multiple plasticity mechanisms.},
  author={Edward S. Boyden and Akira Katoh and Jennifer L. Raymond},
  journal={Annual review of neuroscience},
  year={2004},
  volume={27},
  pages={
          581-609
        }
}
The cerebellum is an evolutionarily conserved structure critical for motor learning in vertebrates. The model that has influenced much of the work in the field for the past 30 years suggests that motor learning is mediated by a single plasticity mechanism in the cerebellum: long-term depression (LTD) of parallel fiber synapses onto Purkinje cells. However, recent studies of simple behaviors such as the vestibulo-ocular reflex (VOR) indicate that multiple plasticity mechanisms contribute to… Expand
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