Cerebellum and M1 interaction during early learning of timed motor sequences

@article{Penhune2005CerebellumAM,
  title={Cerebellum and M1 interaction during early learning of timed motor sequences},
  author={Virginia B. Penhune and Julien Doyon},
  journal={NeuroImage},
  year={2005},
  volume={26},
  pages={801-812}
}

Figures and Tables from this paper

Specific Increases within Global Decreases: A Functional Magnetic Resonance Imaging Investigation of Five Days of Motor Sequence Learning
TLDR
Functional magnetic resonance imaging was used to identify the specific contributions of the cerebellum and primary motor cortex during early learning, consolidation, and retention of a motor sequence task, suggesting that these networks optimize different components of learning.
Short timescale modulation of cortical and cerebellar activity in the early phase of motor sequence learning: an fMRI study
TLDR
This study showed short time scale brain activity modulation in cortical and cerebellar regions with involvement of different brain regions over the learning process not restricted to the motor circuit.
Interaction between Hippocampal and Striatal Systems Predicts Subsequent Consolidation of Motor Sequence Memory
TLDR
The results suggest that the strength of the competitive interplay between the striatum and the hippocampus, participating in the implementation of consistent motor behavior during initial training, appears to be supported by a reorganisation of cerebral activity in hippocampo-neocortical networks after sleep.
Tides of change : identifying the neural correlates of motor sequence learning
TLDR
Results may be interpreted as a shift in activity from the visual to the spatial corticostriatal loop, and are discussed within the context of two current theories of motor sequence learning.
Patterns of Modulation in the Activity and Connectivity of Motor Cortex during the Repeated Generation of Movement Sequences
TLDR
It is proposed that a network including M1 and striatum underlies online motor working memory and may promote a transient integrated representation of a new movement sequence and readily retrieves a previously established movement sequence representation.
The activity in the contralateral primary motor cortex, dorsal premotor and supplementary motor area is modulated by performance gains
TLDR
The results indicate that the amount of activation in the contralateral M1, PMd, and preSMA during the learning of movement sequences is correlated with performance gains and that high level motion features may modulate, or even mask correlations between activity changes and low-level motion attributes.
...
...

References

SHOWING 1-10 OF 78 REFERENCES
Dynamic Cortical and Subcortical Networks in Learning and Delayed Recall of Timed Motor Sequences
TLDR
It is suggested that during early learning cerebellar mechanisms are involved in adjusting movement kinematics according to sensory input to produce accurate motor output and during late learning, the BG may be involved in automatization.
Functional Anatomy of Visuomotor Skill Learning in Human Subjects Examined with Positron Emission Tomography
TLDR
Findings confirm that both the striatum and the cerebellum are involved in the implicit acquisition of a visuomotor skill, especially in the advanced stages of the learning process, and furthermore that the ventrolateral prefrontal cortex contributes preferentially to the declarative aspect of this task.
Long-term adaptation to dynamics of reaching movements: a PET study
Abstract. Positron emission tomography (PET) was used to examine changes in the cerebellum as subjects learned to make movements with their right arm while holding the handle of a robot that produced
Task-Independent Effect of Time on rCBF
TLDR
Analytical strategies are presented to identify experimental effects that are independent of nonspecific time effects, which can be used when it is not possible to control these effects through counterbalancing the experimental design.
Experience-dependent changes in cerebellar contributions to motor sequence learning
TLDR
Results indicate that intrinsic modulation within the cerebellum, in concert with activation of motor-related cortical regions, serves to set up a procedurally acquired sequence of movements that is then maintained elsewhere in the brain.
Cerebellum Activation Associated with Performance Change but Not Motor Learning
TLDR
No cerebellar activation was associated with the learning phase, despite extensive involvement of other cortical and subcortical regions; thus, the cerebellum does not contribute to learning of the motor skill itself but is engaged primarily in the modification of performance.
Functional MRI evidence for adult motor cortex plasticity during motor skill learning
TLDR
A slowly evolving, long-term, experience-dependent reorganization of the adult Ml is suggested, which may underlie the acquisition and retention of the motor skill.
Role of monkey cerebellar nuclei in skill for sequential movement.
TLDR
The results suggest that, among the cerebellar nuclei, the dentate nucleus, especially its dorsal and central regions, is related to the storage and/or retrieval of long-term memory for motor skill.
Functional magnetic resonance imaging of cerebellar activation during the learning of a visuomotor dissociation task
TLDR
The hypothesis that the cerebellum is strongly activated when motor performance is inaccurate, consistent with a role for the cere Bellum in the detection of, and correction for visuomotor errors, is supported.
...
...