Cerebellum Transcriptome of Mice Bred for High Voluntary Activity Offers Insights into Locomotor Control and Reward-Dependent Behaviors

@inproceedings{CaetanoAnolls2016CerebellumTO,
  title={Cerebellum Transcriptome of Mice Bred for High Voluntary Activity Offers Insights into Locomotor Control and Reward-Dependent Behaviors},
  author={Kelsey Caetano-Anoll{\'e}s and Justin S Rhodes and Theodore Garland and Sam D. Perez and Alvaro G. Hernandez and Bruce R. Southey and Sandra L. Rodriguez-Zas},
  booktitle={PloS one},
  year={2016}
}
The role of the cerebellum in motivation and addictive behaviors is less understood than that in control and coordination of movements. High running can be a self-rewarding behavior exhibiting addictive properties. Changes in the cerebellum transcriptional networks of mice from a line selectively bred for High voluntary running (H) were profiled relative to an unselected Control (C) line. The environmental modulation of these changes was assessed both in activity environments corresponding to 7… CONTINUE READING
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