Cerebellar neurodegeneration in the absence of microRNAs

@article{Schaefer2007CerebellarNI,
  title={Cerebellar neurodegeneration in the absence of microRNAs},
  author={Anne Schaefer and D{\`o}nal O' Carroll and Chan Lek Tan and Dean E Hillman and Mutsuyuki Sugimori and Rodolfo Llin{\'a}s and Paul Greengard},
  journal={The Journal of Experimental Medicine},
  year={2007},
  volume={204},
  pages={1553 - 1558}
}
Genome-encoded microRNAs (miRNAs) are potent regulators of gene expression. The significance of miRNAs in various biological processes has been suggested by studies showing an important role of these small RNAs in regulation of cell differentiation. However, the role of miRNAs in regulation of differentiated cell physiology is not well established. Mature neurons express a large number of distinct miRNAs, but the role of miRNAs in postmitotic neurons has not been examined. Here, we provide… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 247 extracted citations

Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2008
View 5 Excerpts
Highly Influenced

Neurodegeneration as an RNA disorder

View 4 Excerpts
Highly Influenced

microRNAs in axon guidance

Front. Cell. Neurosci. • 2014
View 13 Excerpts
Highly Influenced

MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2011
View 4 Excerpts
Highly Influenced

Transgenic Animal Models of Huntington's Disease.

Current topics in behavioral neurosciences • 2011
View 3 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 30 references

A role for Dicer in immune regulation

The Journal of experimental medicine • 2006

Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens.

Proceedings of the National Academy of Sciences of the United States of America • 2006
View 1 Excerpt

A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis.

Proceedings of the National Academy of Sciences of the United States of America • 2005
View 1 Excerpt

Similar Papers

Loading similar papers…