Cerebellar mechanisms in eyeblink conditioning.

  title={Cerebellar mechanisms in eyeblink conditioning.},
  author={Philip J E Attwell and Magnus Ivarsson and Laurie Millar and Christopher H. Yeo},
  journal={Annals of the New York Academy of Sciences},
A recent model of cerebellar learning in eyeblink conditioning predicts two sites of plasticity, the cerebellar cortex and cerebellar nuclei, which store information relating to timing and driving the movement, respectively. Consistent with this idea, lesions of the cortex or reversible "disconnections" of Purkinje cell output to the nuclei have been shown to disrupt response timing to produce short-latency conditioned eyeblinks. To better characterize potential cortical and nuclear… CONTINUE READING