Cerebellar hypermetria is larger when the inertial load is artificially increased

@article{Manto1994CerebellarHI,
  title={Cerebellar hypermetria is larger when the inertial load is artificially increased},
  author={Mario Manto and Emile Godaux and Jean Jacquy},
  journal={Annals of Neurology},
  year={1994},
  volume={35}
}
Hypermetria is a classical cerebellar symptom designating the overshoot observed when a patient is asked to make a very fast and accurate movement. The movement studied here was wrist flexion. Hypermetria was found to be increased by artificially increasing the inertia of the moving hand. A normal subject adapted himself to increasing inertia by increasing both his agonist activity (the launching force) and its antagonist activity (the braking force). In the same circumstances, a patient with… 
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References

SHOWING 1-10 OF 13 REFERENCES
Physiological analysis of simple rapid movements in patients with cerebellar deficits.
TLDR
In patients with cerebellar deficits, the first agonist burst of the biceps was frequently prolonged regardless of the distance or speed of the movement, and the most striking kinematic abnormality was prolonged acceleration time.
EMG analysis of patients with cerebellar deficits.
EMGs from biceps and triceps were recorded during stereotyped elbow flexion tasks performed by 20 patients fulfilling clinical criteria for 'cerebellar deficits' and the data were compared with…
Cerebellar dysmetria at the elbow, wrist, and fingers.
TLDR
Cerebellar patients with dysmetria showed hypermetria followed by tremor at all three joints when movements were made with the manipulanda, and an asymmetry with decreased peak accelerations and increased peak decelerations compared to normal movements could be used clinically as sensitive indicators of cerebellar dysfunction.
Movement and electromyographic disorders associated with cerebellar dysmetria.
TLDR
It is concluded that normal function of the cerebellum is necessary for the generation of agonist and antagonist muscle activity that is both of the appropriate magnitude and timing to control the dynamic phase of arm movements.
Modification of Intention Tremor in Man
TLDR
T HE tremor observed in patients with Parkinson's disease is present at rest, and may be markedly attenuated during voluntary movement, and whether the sensory feedback of patients with abnormalities of motor control is different from that of normal subjects is attempted.
Ballistic flexion movements of the human thumb.
TLDR
It is concluded that the individual components of a ballistic movement are relatively fixed in duration and the amount of e.m. activity is altered within this time interval to produce the different forces required for fast movements of different amplitude.
The trajectory of human wrist movements.
TLDR
It is concluded that minimization of jerk is not a general principle used by the nervous system in organizing voluntary movements, although movements may approach the predicted form, particularly under inertial loading conditions.
Roles of the elements of the triphasic control signal
Effects of dentate cooling on rapid alternating arm movements.
THE CEREBELLUM OF MAN
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