Cerebellar dysfunction during high dose cytosine arabinoside therapy in a case of acute myelogenous leukaemia.

  • Søren Cold
  • Published 1986 in Scandinavian journal of haematology
A case of persistent cerebellar toxicity following systemic high dose cytosine arabinoside (HDCA) treatment of acute myelogenous leukaemia is reported. The symptoms, which developed at a cumulative dose of 32 g/m2, subsided to some extent following discontinuation of the drug, but left signs of cerebellar dysfunction 10 months later. A review of previously… CONTINUE READING