Cerebellar contributions to cognitive functions: A progress report after two decades of research

  title={Cerebellar contributions to cognitive functions: A progress report after two decades of research},
  author={Dagmar Timmann and Irene Daum},
  journal={The Cerebellum},
Accumulating evidence from both human lesion and functional neuroimaging studies appears to support the hypothesis that the cerebellum contributes to non-motor functions. Along similar lines, cognitive, affective and behavioural changes in psychiatric disorders, such as autism, schizophrenia and dyslexia, have been linked to structural cerebellar abnormalities. The aim of this special issue was to evaluate the current knowledge base after more than 20 years of controversial discussion. The… 

Review article The role of the cerebellum in control of cognitive functions – neuropsychological perspective

The lesions of particular parts of the cerebellum are connected with cognitive dysfunctions typical for these which are observed in cerebral damage (especially frontal and parietal cortical parts), which confirms the functional role of the Cerebello-cortical loops in cognitive processes.

How Consistent are Cognitive Impairments in Patients with Cerebellar Disorders?

The review suggests that the inconsistencies in cognitive impairments may offer clues as to the nature of cerebellar cognitive involvement and in children, in particular with congenital disease.

Mechanisms of cerebellar involvement in associative learning

The Cognitive Face of Cerebellum; Implications for Extended Research

This review has been an effort to discuss the studies assessing different aspects of cognitive and affective disorders following cerebellar damage, as well as the Cerebellar activity during cognitive tasks using novel approaches including fMRI and PET scans.

The cerebellar cognitive profile.

Of the various cognitive domains, the ability to sequence was the most adversely affected in nearly all subjects, supporting the hypothesis that sequencing is a basic cerebellar operation.

Neuropsychological disorders induced by cerebellar damage.

Cognitive sequencing impairment in patients with focal or atrophic cerebellar damage.

The present data support the hypothesis that sequence processing is the cerebellar mode of operation also in the cognitive domain and indicate that patients with cerebro-cerebellar damage present a cognitive sequencing impairment independently of lesion type or localization.

Anatomical Correlate of Impaired Covert Visual Attentional Processes in Patients with Cerebellar Lesions

It is suggested that midcerebellar regions are indirectly involved in covert visual attention via oculomotor control mechanisms, and specific cerebellar structures do influence attentional orienting, whereas others do not.

Cerebellar Functional Lateralization From the Perspective of Clinical Neuropsychology

Objective: The cerebellar functional laterality, with its right hemisphere predominantly involved in verbal performance and the left one engaged in visuospatial processes, has strong empirical

Cerebellar contribution to cognitive, emotional, and behavioural functions in children with cerebellar abnormalities

  • S. Misciagna
  • Psychology, Biology
    Developmental medicine and child neurology
  • 2011
The results show that proximal lesions of the dentato-thalamo-cortical pathway may lead to a functional disconnection between the cerebellum and the associate cortical regions and, subsequently, cause the characteristic neurocognitive impairment in the posterior fossa syndrome.



Cerebellar lesion studies of cognitive function in children and adolescents — limitations and negative findings

It is demonstrated that many findings frequently cited to support cerebellar involvement in cognition are insufficient to prove the hypothesis that the cerebellum contributes to a wide range of non-motor functions, including attention, language and visuospatial functions.

Thinking about the cerebellum.

  • M. Glickstein
  • Psychology, Biology
    Brain : a journal of neurology
  • 2006
The paper by Susan Ravizza and colleagues in this issue of Brain reports the results of a series of studies comparing the performance of cerebellar patients with that of normal control subjects on short-term memory tasks.

The attentive cerebellum — myth or reality?

The concept of attentional dysmetria as a consequence of cerebellar damage is not adequately supported because disturbances have only been observed consistently for tasks involving significant oculomotor, motor, and working memory demands.

Cerebellar involvement in executive control

The role of the cerebellum in executive processing is focused on, reviewing findings derived from neuroimaging studies or from studies investigating deficits related to cerebellar dysfunction, and methodological problems in assessing executive deficits in general and in assessing the Cerebellar contribution to executive processing in particular are addressed.

The cerebellum in cognitive processes: Supporting studies in children

The cerebellum seems to play an important role in many higher cognitive functions especially in learning, and there is a suggestion that the earlier the incorrect influence the more pronounced the problems.

The cerebellum and motor dysfunction in neuropsychiatric disorders

This review finds evidence of motor dysfunction associated with neuropsychiatrie disorders consistent with disruption of cerebellar motor function in autism, schizophrenia and dyslexia, but it is cautioned that the restricted set of motor symptoms does not suggest global Cerebellar dysfunction.

Cerebellar contributions to verbal working memory: beyond cognitive theory

It is argued that general theories of cerebellar function adapted from the motor literature may also provide a useful framework to understand the non-motor contributions of the cerebellum to verbal working memory.

The contribution of the cerebellum to speech production and speech perception: Clinical and functional imaging data

A prearticulatory verbal code bound to reciprocal right Cerebellar/left frontal interactions might represent a common platform for a variety of cerebellar engagements in cognitive functions.

On the mechanism of cerebellar contributions to cognition

The intrinsic circuitry suggests that the cerebellar cortex links together and combines nuclear output activities, which is consistent with the motor deficits in coordination after midline vermal section in humans and Purkinje cell recording in trained animals.

The neuropsychiatry of the cerebellum — insights from the clinic

The broader role of the cerebellum in the pathogenesis of these neuropsychiatric symptoms is discussed, and the possibility of using cerebellar stimulation to treat psychiatric disorders by enhancing Cerebellar modulation of cognition and emotion is revisited.