Cerebellar aminergic neuromodulation: towards a functional understanding

  title={Cerebellar aminergic neuromodulation: towards a functional understanding},
  author={N. Schweighofer and K. Doya and Shinya Kuroda},
  journal={Brain Research Reviews},
  • N. Schweighofer, K. Doya, Shinya Kuroda
  • Published 2004
  • Psychology, Medicine
  • Brain Research Reviews
  • Although a number of neuromodulators influence the cerebellar circuitry, their functions remain largely unknown. By reviewing and combining results from data-driven and theory-driven studies, we attempt to provide an integrated systems view of cerebellar neuromodulation. First, we review the short- and long-term effects of neuromodulators on the cerebellar circuitry. Second, we review recent theories of the cerebellum and show that a number of modulatory signals are needed for powerful… CONTINUE READING
    127 Citations
    Functional roles of neuropeptides in cerebellar circuits
    • M. Ito
    • Biology, Medicine
    • Neuroscience
    • 2009
    • 41
    In and out of the loop: external and internal modulation of the olivo-cerebellar loop
    • 8
    • PDF
    The cholinergic system in the cerebellum: from structure to function
    • 13
    Cerebellar circuitry as a neuronal machine
    • M. Ito
    • Psychology, Medicine
    • Progress in Neurobiology
    • 2006
    • 660
    Gating of Long-Term Potentiation by Nicotinic Acetylcholine Receptors at the Cerebellum Input Stage
    • 52
    • PDF
    Histaminergic afferent system in the cerebellum: structure and function
    • 20
    The role of the serotonergic system in motor control
    • 11
    • Highly Influenced
    The cerebellum on cocaine: plasticity and metaplasticity
    • 31
    • PDF


    Motor learning deficits in aged rats are correlated with loss of cerebellar noradrenergic function
    • 103
    Serotonin-Driven Long-Range Inhibitory Connections in the Cerebellar Cortex
    • 149
    • PDF
    Diffusion of nitric oxide can facilitate cerebellar learning: A simulation study.
    • N. Schweighofer, G. Ferriol
    • Medicine, Chemistry
    • Proceedings of the National Academy of Sciences of the United States of America
    • 2000
    • 48
    • PDF
    Serotonergic control of cerebellar mossy fiber activity by modulation of signal transfer by rat pontine nuclei neurons.
    • 5
    • PDF
    The cerebellar serotoninergic system and its possible involvement in cerebellar ataxia.
    • P. Trouillas
    • Medicine
    • The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
    • 1993
    • 30
    • PDF
    A Theory of Cerebellar Function
    • 2,306
    • Highly Influential
    • PDF
    Metalearning and neuromodulation
    • K. Doya
    • Mathematics, Computer Science
    • Neural Networks
    • 2002
    • 585
    • PDF
    Monoaminergic long-term facilitation of GABA-mediated inhibitory transmission at cerebellar synapses
    • 75
    • Highly Influential
    A model of cerebellar metaplasticity.
    • 42
    • PDF
    Cellular mechanisms of cerebellar LTD
    • 261
    • Highly Influential