Cerebellar Purkinje cell activity drives motor learning

  title={Cerebellar Purkinje cell activity drives motor learning},
  author={Td Barbara Nguyen-Vu and Rhea R. Kimpo and Jacob M Rinaldi and Arunima Kohli and Hongkui Zeng and Karl Deisseroth and Jennifer L. Raymond},
  journal={Nature Neuroscience},
The climbing fiber input to the cerebellar cortex is thought to provide instructive signals that drive the induction of motor skill learning. We found that optogenetic activation of Purkinje cells, the sole output neurons of the cerebellar cortex, can also drive motor learning in mice. This dual control over the induction of learning by climbing fibers and Purkinje cells can expand the learning capacity of motor circuits. 
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