Cerebellar AMPA/KA receptor antagonism by CNQX inhibits vestibuloocular reflex adaptation

  title={Cerebellar AMPA/KA receptor antagonism by CNQX inhibits vestibuloocular reflex adaptation},
  author={Troy L. Carter and James G. Mcelligott},
  journal={Experimental Brain Research},
Vestibuloocular reflex (VOR) performance and adaptation have been investigated during antagonism of cerebellar AMPA/quisqualate and kainate receptors (AMPA/KA) by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX). Injection of CNQX into the vestibulo-cerebellum of the goldfish before adaptation significantly inhibited and, at the highest dosage, completely prevented acquisition of adaptive reflex gain increases and decreases during a 3-h training period. Injection of CNQX before initiation of VOR… 

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