Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo.

@article{Tavares2007CerberusIA,
  title={Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo.},
  author={Ana Teresa Tavares and Sofia M. Andrade and Ana Cristina C. Silva and Jos{\'e} Ant{\'o}nio Belo},
  journal={Development},
  year={2007},
  volume={134 11},
  pages={2051-60}
}
The TGF-beta-related molecule Nodal plays an essential and conserved role in left-right patterning of the vertebrate embryo. Previous reports have shown that the zebrafish and mouse Cerberus-related proteins Charon and Cerberus-like-2 (Cerl-2), respectively, act in the node region to prevent the Nodal signal from crossing to the right side, whereas chick Cerberus (cCer) has an unclear function in the left-side mesoderm. In this study, we investigate the transcriptional regulation and function… CONTINUE READING

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