Ceramide concentrations in septic patients: a possible marker of multiple organ dysfunction syndrome.

  title={Ceramide concentrations in septic patients: a possible marker of multiple organ dysfunction syndrome.},
  author={Giovanna Delogu and Giuseppe Famularo and Francesca Amati and Luciano Signore and Adriana Antonucci and Vincenzo Trinchieri and Luisa Di Marzio and Maria Grazia Cifone},
  journal={Critical care medicine},
  volume={27 11},
OBJECTIVES To investigate the concentrations of mononuclear cell-associated ceramide and serum tumor necrosis factor-alpha (TNF-alpha) in patients with sepsis and to assess their predictive value for the development of multiple organ dysfunction syndrome (MODS). DESIGN Prospective, cohort study. SETTING Intensive care unit and two research laboratories at a university hospital. PATIENTS Twenty-three adult patients admitted to an intensive care unit meeting the criteria for diagnosis of… CONTINUE READING

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