Ceramide and raft signaling are linked with each other in UVA radiation-induced gene expression

Abstract

Solar ultraviolet A (UVA) (320–400 nm) radiation-induced gene expression in keratinocytes is initiated at the level of the cell membrane via generation of singlet oxygen and subsequent formation of ceramide from sphingomyelin. We now report that the UVA response also involves raft signaling and that ceramide and raft signaling are linked with each other… (More)
DOI: 10.1038/onc.2008.116

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