Ceramide and ceramide 1-phosphate in health and disease

Abstract

Sphingolipids are essential components of cell membranes, and many of them regulate vital cell functions. In particular, ceramide plays crucial roles in cell signaling processes. Two major actions of ceramides are the promotion of cell cycle arrest and the induction of apoptosis. Phosphorylation of ceramide produces ceramide 1-phosphate (C1P), which has… (More)
DOI: 10.1186/1476-511X-9-15

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