Cepharanthine alleviates liver injury in a rodent model of limb ischemia-reperfusion.

Abstract

OBJECTIVES Limb ischemia-reperfusion (I/R) causes remote organ injury (e.g., liver injury). Oxidation and inflammation are crucial mechanisms. We investigated the effects of cepharanthine, a potent antioxidative and anti-inflammatory drug, on alleviating liver injury induced by limb I/R. METHODS Twenty-four adult male Sprague-Dawley rats were randomized… (More)
DOI: 10.1016/j.aat.2015.11.004

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