Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation

@article{Oshimori2009Cep72RT,
  title={Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation},
  author={Naoki Oshimori and X. Li and M. Ohsugi and T. Yamamoto},
  journal={The EMBO Journal},
  year={2009},
  volume={28}
}
  • Naoki Oshimori, X. Li, +1 author T. Yamamoto
  • Published 2009
  • Biology, Medicine
  • The EMBO Journal
  • Microtubule‐nucleation activity and structural integrity of the centrosome are critical for various cellular functions. The γ‐tubulin ring complexes (γTuRCs) localizing to the pericentriolar matrix (PCM) of the centrosome are major sites of microtubule nucleation. The PCM is thought to be created by two cognate large coiled‐coil proteins, pericentrin/kendrin and CG‐NAP/AKAP450, and its stabilization by Kizuna is essential for bipolar spindle formation. However, the mechanisms by which these… CONTINUE READING
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    References

    SHOWING 1-10 OF 40 REFERENCES
    Human Cep192 Is Required for Mitotic Centrosome and Spindle Assembly
    • 157
    Mitosis-specific anchoring of gamma tubulin complexes by pericentrin controls spindle organization and mitotic entry.
    • 277
    CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex.
    • 189
    • PDF
    Microtubule nucleation by γ-tubulin-containing rings in the centrosome
    • 473
    • PDF
    The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity
    • 144
    GCP-WD is a γ-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation
    • 296
    • PDF
    Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.
    • 240
    Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.
    • 137
    The Mammalian SPD-2 Ortholog Cep192 Regulates Centrosome Biogenesis
    • 152
    • PDF