Cep164 mediates vesicular docking to the mother centriole during early steps of ciliogenesis

@inproceedings{Schmidt2012Cep164MV,
  title={Cep164 mediates vesicular docking to the mother centriole during early steps of ciliogenesis},
  author={Kerstin N. Schmidt and Stefanie Kuhns and Annett Neuner and Birgit Hub and H. Zentgraf and Gislene Pereira},
  booktitle={The Journal of cell biology},
  year={2012}
}
Cilia formation is a multi-step process that starts with the docking of a vesicle at the distal part of the mother centriole. This step marks the conversion of the mother centriole into the basal body, from which axonemal microtubules extend to form the ciliary compartment. How vesicles are stably attached to the mother centriole to initiate ciliary membrane biogenesis is unknown. Here, we investigate the molecular role of the mother centriolar component Cep164 in ciliogenesis. We show that… CONTINUE READING
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